منابع مشابه
Virulence Factors Variation Among Bordetella Pertussis Isolates in Iran
Pertussis is still endemic and the recently resurgence of the disease caused by Bordetella pertussis has been shown in many countries. The polymorphism of the virulence genes of B. pertussis and lack of any information about the allelic variation between the Iranian isolates promotes us to analysis of the genes encoded virulence factors including ptxS1, prn, fim3 and cya to understand the diffe...
متن کاملTn5-induced mutations affecting virulence factors of Bordetella pertussis.
Transposon Tn5 was used to isolate mutants of Bordetella pertussis. Strains with Tn5 insertions were screened for loss of virulence-associated factors, including filamentous hemagglutinin, hemolysin, and pertussis toxin. Several mutants deficient for hemolysin production were obtained. All produced dermonecrotic toxin, pertussis toxin, and filamentous hemagglutinin, but were found to vary with ...
متن کاملRegulatory factors of Bordetella pertussis affecting virulence gene expression.
Most pathogenic bacteria encounter changing growth conditions during their infectious cycle and, accordingly, have to modulate gene expression to enable the efficient colonization of different environments outside or within their host organisms. In Bordetella pertussis the transcription of most virulence factors including several toxins and adhesins is regulated coordinately by the BvgAS two-co...
متن کاملVirulence Factors Variation Among Bordetella Pertussis Isolates in Iran
∗ Corresponding author: Pertussis Reference Laboratory, Department of Bacteriology and Microbiology Research Center, Pasteur Institute of Iran. Email: [email protected] ertussis or whooping cough, caused by Bordetella pertussis, is one of the important vaccine preventable diseases. Pertussis vaccination is recommended as a part of routine childhood immunization. The whole cell per...
متن کاملBordetella pertussis virulence factors affect phagocytosis by human neutrophils.
The interaction between human neutrophils and wild-type Bordetella pertussis or mutants expressing altered lipopolysaccharide or lacking virulence factors-pertussis toxin, adenylate cyclase toxin, dermonecrotic toxin, filamentous hemagglutinin (FHA), pertactin, or BrkA-was examined. In the absence of antibodies, the wild-type strain and the mutants, with the exception of mutants lacking FHA, at...
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ژورنال
عنوان ژورنال: Nippon Saikingaku Zasshi
سال: 1996
ISSN: 1882-4110,0021-4930
DOI: 10.3412/jsb.51.737